Fig. 3: Aβ42-mediated inhibition of LTP is rescued by RSLA but not TAK-242 treatment. | Communications Biology

Fig. 3: Aβ42-mediated inhibition of LTP is rescued by RSLA but not TAK-242 treatment.

From: Beta amyloid aggregates induce sensitised TLR4 signalling causing long-term potentiation deficit and rat neuronal cell death

Fig. 3

Top: Example traces of fEPSPs from indicated time-points. Bottom: Mean fEPSP slope shown as percentage of the normalised baseline. a The inhibition of LTP by application of oligomerised Aβ42 (5 nM oligomers and 500 nM total monomer) was prevented by RSLA. b TAK-242 had no effect on Aβ-mediated inhibition of LTP. c TAK-242 and RSLA had no effect on the expression of LTP compared with control. All symbols represent the mean ± sem.

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