Fig. 1: Detecting the Dex response in single cells. | Communications Biology

Fig. 1: Detecting the Dex response in single cells.

From: Single-cell RNA sequencing reveals a heterogeneous response to Glucocorticoids in breast cancer cells

Fig. 1

a, b Violin plot of unique transcripts per cell and detected genes per cell in scRNAseq dataset. Each dot represents a single cell. Four-hundred cells were examined at each timepoint. c Pie chart depicting all genes/genomic features expressed in bulk RNAseq and the proportion detected by scRNAseq. d Plot depicting the percentage of genes from each bulk RNAseq expression quintile that are detected in scRNAseq (black dots) and box + whiskers depicting the range of detection rates for each gene in the scRNAseq. e Expression patterns for PNMT, TSC22D3, and GLUL across the Dex time course in the bulk RNAseq. Asterisks = p-value < 0.05. f–h Scaled Log10 expression (box and scatter plots) and ratio of expressing cells (black dot/line plot) for PNMT, TSC22D3, and GLUL in scRNAseq. Each dot in the scatter plot represents an individual cell.

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