Table 1 Patient characteristics in discovery and validation sets.
From: A miRNA-based diagnostic model predicts resectable lung cancer in humans with high accuracy
Variables | Discovery set (N = 416) | Validation set (N = 3328) | ||||
|---|---|---|---|---|---|---|
|  | Lung cancer (N = 208) | Non-cancer (N = 208) | P Value | Lung cancer (N = 1358) | Non-cancer (N = 1970) | P Value |
Age, years ± SD | 60.2 ± 0.5 | 60.0 ± 0.5 | 0.7843 | 66.3 ± 0.3 | 50.3 ± 0.2 | <0.001 |
Sex, n (%) | ||||||
 Men | 113 (54.3) | 103 (50.0) | 0.377 | 782 (57.6) | 1026 (52.1) | 0.002 |
 Women | 95 (45.7) | 105 (50.0) |  | 576 (42.4) | 944 (47.9) |  |
Smoking status, n (%) | ||||||
 Former or current | 84 (40.4) | 83 (40.0) | 1.0 | 888 (65.4) | 399 (20.3) | <0.001 |
 Never | 124 (59.6) | 125 (60.1) |  | 470 (34.6) | 1571 (79.7) |  |
Histology, n (%) | ||||||
 Adenocarcinoma | 179 (86.1) | – | – | 1038 (76.4) | – | – |
 Squamous carcinoma | 14 (6.7) | – | – | 207 (15.2) | – | – |
 Adenosquamous carcinoma | 1 (0.5) | – | – | 17 (1.3) | – | – |
 Small cell carcinoma | 1 (0.5) | – | – | 22 (1.6) | – | – |
 Other | 13 (6.3) | – | – | 74 (5.4) | – | – |
Stage, n (%) | ||||||
 I (IA+ IB) | 155 (74.5) | – | – | 971 (71.5) | – | – |
 II (IIA+ IIB) | 26 (12.5) | – | – | 207 (15.2) | – | – |
 III (IIIA+ IIIB) | 22 (10.6) | – | – | 170 (12.5) | – | – |
 IV | 3 (1.4) | – | – | 8 (0.6) | – | – |
 0 | 2 (1.0) | – | – | 2 (0.1) | – | – |
