Fig. 6: Asymmetric size reduction in Tps1 mutants is caused by changes in both cell size and cell number.
a Merged images of left (red) and right (blue) wings from control and Tps1MIC mutant males. b The size differences between left (L) and right (R) wings for individual flies. The purple and green lines mark two extreme cases. c The red squares indicate the regions used for the measurement of cell size. Both dorsal and ventral sides for each region were analyzed: in total, 10 areas in each wing were analyzed. d Relative ratios for cell size and cell number between left and right wings in each area. The average values for the larger side (left wing for case 1 and right wing for case 2) were set to 1. e Normalized differences in wing size, cell size, and cell number, modified from the data shown in (d). f The size differences between left and right wings in individual flies. Four randomly selected samples for each dietary condition are shown. g Relative ratios for cell size and cell number between the left and right wings of individual flies. *p < 0.05, **p < 0.01; paired two-tailed Student’s t-test (d, g).
