Table 3 Phenotypic associations between sleep indices and cortical thickness are mirrored by genetic correlations.

From: The interrelation of sleep and mental and physical health is anchored in grey-matter neuroanatomy and under genetic control

Phenotypic correlation, Fig. 1b (HCP)

Left superior frontal gyrus

 

p

HCP (total sample) (n = 1113)

   r = −0.10

0.0013*

Genetic correlation (HCP)

ρg = −0.27

0.035*

Environmental correlation (HCP)

ρe = 0.02

0.97

Phenotypic correlation, Fig. 1e (eNKI)

Left inferior temporal cortex

 

p

HCP (total sample) (n = 1113)

   r = 0.04

0.14

Genetic correlation (HCP)

ρg = −0.09

0.67

Environmental correlation (HCP)

ρe = 0.06

0.27

Right occipital cortex

 

p

HCP (total sample) (n = 1113)

   r = 0.04

0.20

Genetic correlation (HCP)

ρg = 0.28

0.03*

Environmental correlation (HCP)

ρe = −0.08

0.19

Right inferior temporal cortex

 

p

HCP (total sample) (n = 1113)

   r = 0.004

0.90

Genetic correlation (HCP)

ρg = 0.38

0 .02*

Environmental correlation (HCP)

ρe = −0.11

0.06

  1. Genetic and environmental correlation between sleep and thickness in FDR-corrected ROIs from phenotypic correlational analysis in Fig. 1. Asterisks (**) indicates to significant correlation (q < 0.05) and asterisk (*) indicates association at trend-level p < 0.05.
Back to article page