Table 2 Zone of clearance (mm) and phenotypic resistance determination for clinical Pseudomonas aeruginosa isolates.

From: Tetracycline-inactivating enzymes from environmental, human commensal, and pathogenic bacteria cause broad-spectrum tetracycline resistance

 

Pa-3

Pa-8

ATCC 27853

Antibiotic

Kirby–Bauer (mm)

Interpretation

Kirby–Bauer (mm)

Interpretation

Kirby–Bauer (mm)

Delafloxacin

6

Resistant

6

Resistant

23–29

Ceftazidime

6

Resistant

6

Resistant

22–29

Cefepime

6

Resistant

6

Resistant

25–31

Meropenem

6

Resistant

6

Resistant

27–33

Imipenem

6

Resistant

25

Sensitive

20–28

Piperacillin/tazobactam

24

Sensitive

19

Intermediate

25–33

Ceftolozane/tazobactam

6

Resistant

29

Sensitive

25–31

Ceftazidime/avibactam

6

Resistant

26

Sensitive

25–31

Ciprofloxacin

6

Resistant

6

Resistant

25–33

Levofloxacin

6

Resistant

6

Resistant

19–26

Gentamicin

6

Resistant

6

Resistant

17–23

Amikacin

6

Resistant

17

Sensitive

18–26

Trimethoprim/sulfamethoxazole

6

NA

6

NA

—

Fosfomicin

12

Resistant

15

Intermediate

—

Colistin

13

Sensitive

15

Sensitive

11–17

Aztreonam

17

Intermediate

16

Intermediate

23–29

Doxycycline

6

NA

6

NA

—

Minocycline

6

NA

6

NA

—

Tigecycline

6

NA

6

NA

9–13

Nitrofurantoin

6

NA

6

NA

—

Carbapenem inactivation assay

14

Positive

27

Positive

—

  1. NA indicates that no interpretive criteria have been established. ATCC 27853 values are disk diffusion QC ranges provided by the CLSI63.