Fig. 4: In vitro experiments with CSPM@CpG. | Communications Biology

Fig. 4: In vitro experiments with CSPM@CpG.

From: A Cu9S5 nanoparticle-based CpG delivery system for synergistic photothermal-, photodynamic- and immunotherapy

Fig. 4

a Detection of intracellular ROS in 4T1 cells of PBS group and different concentrations of CSPM@CpG groups under 650 nm laser irradiation at 1 W cm−2 for 5 min. Scale bar: 100 μm. b Cell viability of 4T1 cells incubated with different concentrations of CSPM@CpG NPs under PDT treatment (650 nm, 1 W cm−2, 5 min), PTT treatment (808 nm, 2 W cm−2, 5 min), and combined PDT treatment and PTT treatment. c The secretion of IL-12 from DC 2.4 cells stimulated with different treatments. The concentration of CpG was consistent with that loaded in the CSMP@CpG. Data are presented as means ± standard deviation (s.d.; n = 3). p values *<0.05, **<0.01, ***<0.001, ****<0.0001.

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