Fig. 3: The distribution of TcdB subtypes in the phylogeny of STs. | Communications Biology

Fig. 3: The distribution of TcdB subtypes in the phylogeny of STs.

From: Subtyping analysis reveals new variants and accelerated evolution of Clostridioides difficile toxin B

Fig. 3

A maximum likelihood tree was built for 110 C. difficile MLST types based on seven housekeeping genes (adk, atpA, dxr, glyA, recA, sodA, and tpi). Each color in the nodes represents one subtype of TcdB (TcdB1 in pink, TcdB2 in light blue, TcdB3 in lavender, TcdB4 in yellow, TcdB5 in green, TcdB6 in aubergine, TcdB7 in orange and TcdB8 in brown). TcdB1b and TcdB1c were denoted with one and two dots. C. difficile clade 1–5 were denoted by colored arcs. ST122, ST200, ST360, and ST361 are marked as outliers (red arcs). The red arrows and boxes highlight two C. difficile MLST types that contain either TcdB2 or TcdB4 in different isolates.

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