Table 1 Minimum between-subtype amino-acid differences among TcdB subtypes.

From: Subtyping analysis reveals new variants and accelerated evolution of Clostridioides difficile toxin B

Subtype

Numbers of strains

Minimum between-subtype differences (%)

Maximum within-subtype difference (%)

Representative strain

TcdB1

TcdB2

TcdB3

TcdB4

TcdB5

TcdB6

TcdB7

TcdB8

TcdB1

n = 1639

5.33

5.75

11.15

5.70

10.06

10.48

6.72

4.14

630

TcdB2

n = 678

 

10.10

5.15

11.24

6.00

5.75

8.92

4.27

CD196

TcdB3

n = 333

  

6.38

5.03

13.44

13.77

12.13

0.85

1470

TcdB4

n = 29

   

8.96

9.63

8.32

13.48

3.93

8864

TcdB5

n = 7

    

14.32

14.32

12.17

0.17

ES130

TcdB6

n = 1

     

5.92

11.33

CD160

TcdB7

n = 3

      

11.62

0.17

CD10–165

TcdB8

n = 1

       

173070