Fig. 3: In vivo whole-cell recording from granule cells revealed convergent synaptic inputs.

a Representative recordings; simultaneous field potential recording from S1 (top) and whole-cell voltage clamp recordings from granule cell (lower); 20 consecutive traces are overlaid. The averaged traces are in red. Detected EPSC events are shown in raster plots (middle) and time histograms (bottom). Green and brown bars indicate the early and the late phases, respectively. Trials under control (left) and the light (right) conditions were interleaved. b Numbers of evoked EPSC events in the early and the late phases were compared in 24 cells. The numbers were corrected for baseline spontaneous events by subtraction in this and the following panels. For qualitative description, event numbers of <0.5 events/trial (dotted lines) were defined as no response. Error bars indicate SEMs (trial-by-trial fluctuation). The arrow points to the cell recorded in a. c Median interevent intervals of each cell were compared (n = 11, early; n = 15, late). d Trial-by-trail fluctuations (measured as standard deviations) of the timing of the first event during each time period were compared (n = 15, early; n = 16, late). e Mean amplitudes of individual EPSCs in the early and late phases were compared (n = 15, early; n = 16, late). f EPSC event numbers were compared for the early phase (left) and the late phase (right) (n = 24). Means ± SEMs are presented as black lines and bars, respectively.