Fig. 6: Effects of S1 photoinhibition on SS and CS in Purkinje cells. | Communications Biology

Fig. 6: Effects of S1 photoinhibition on SS and CS in Purkinje cells.

From: Multiple signals evoked by unisensory stimulation converge onto cerebellar granule and Purkinje cells in mice

Fig. 6

a Representative extracellular unit recordings of a Purkinje cell; five traces are displayed (top). Simultaneous field potential recordings from S1 are provided in Supplementary Data 1. SS (black) and CS (red) are plotted in the raster plots (lower). Separate time histograms of SS (middle) and CS (bottom) from 40 trials of each condition are shown. b Enlarged views of SS and CS of the unit shown in a; six traces in each were aligned and overlaid. c Averaged time histograms of SS (1 ms bin) and CS (2 ms bin) from 20 Purkinje cells. Shading indicates SEMs. Vertical dotted lines indicate the onset of stimulation as in a. d Spike numbers were measured during the times (1–5) indicated by colored bars in c. Means ± SEMs are presented as black lines and bars, respectively. e Bubble size indicates magnitude of inhibition of the cerebellar CS when the blue light was applied to each spot in the right cerebral hemisphere. The magnitude of inhibition significantly correlated with the size of field potential at each spot (P = 0.011, n = 5 spots). Data from six animals were combined. Each spot is the average from 3–6 animals.

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