Fig. 7: Elevated cytoplasmic Kaiso, LC3A/B, and race are associated with an immune-suppressive tumor microenvironment. | Communications Biology

Fig. 7: Elevated cytoplasmic Kaiso, LC3A/B, and race are associated with an immune-suppressive tumor microenvironment.

From: Kaiso (ZBTB33) subcellular partitioning functionally links LC3A/B, the tumor microenvironment, and breast cancer survival

Fig. 7

a Representative multi-spectral quantitative immunofluorescence (mQIF) of the tumor microenvironment of a breast cancer TMA core, stained for pan-cytokeratin (Cy7, cyan); PDL-1 (Cy5, red); CD8 (FITC, green); CD68 (TRITC, carmine). b Coordinate map for nearest-neighbor analysis of tumor and stromal immunophenotypes. c Nearest-neighbor analysis showing the frequency distribution of immune cell proximities to tumor-associated with expression quartiles (Q1–Q4) of cytoplasmic Kaiso, LC3A/B, nuclear Kaiso, and race (white versus black).

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