Table 1 Crystallographic data collection and refinement statistics.

From: Molecular mechanism and structural basis of small-molecule modulation of the gating of acid-sensing ion channel 1

 

ΔASIC1/JNJ-799760a

Data collection

 

Space group

P212121

Cell dimensions

 

  a, b, c (Å)

91.79, 116.15, 227.79

 α, β, γ (°)

90, 90, 90

Resolution (Ã…)

3.0 (3.1–3.0)b

Rsym or Rmerge

0.153 (0.783)

I/σI

11.1 (1.7)

Completeness (%)

98.10 (87.39)

Redundancy

5.0 (3.6)

Refinement

 

Resolution (Ã…)

35.2–3.0

No. of reflections

48,177 (4219)

Rwork/Rfree

0.224/0.267

No. of atoms

 

 Protein

9697

 Ligand/ion

130

 Water

 0

B-factors

 

 Protein

79.98

 Ligand/ion

90.71

 Water

 -

R.m.s. deviations

 

 Bond lengths (Å)

0.011

 Bond angles (°)

1.35

  1. aOne crystal was used for data collection.
  2. bValues in parentheses are for the highest-resolution shell.
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