Fig. 2: Compositional differences of the gut microbiome in short and long-term survivors.

a The different abundance of bacterial taxa between the two groups were identified by LEfSe. It was significantly different when alpha value of the factorial Kruskal–Wallis test was <0.05 and the logarithmic LDA score was >3.5. The left histogram showed the LDA scores of taxa differentially abundant between the two groups. The taxonomy was listed, followed by its core group. Putative species (Specific OTUs) identified as significantly more enriched/depleted (Fisher/Wilcoxon test p value < 0.05) in patients with short-term vs long-term in baseline samples. b Cladogram representation of the significantly different taxa features from phylum (inner circle) to genus (outer circle). c The right heatmap showed the relative abundance of specific bacteria by phylum, class, order, family, and genus between short-term and long-term survivors.