Table 3 Top ten genes enriched with SNPs signals (MAGMA).

From: Identification of genetic factors influencing metabolic dysregulation and retinal support for MacTel, a retinal disorder

Symbol

Chr

Start

Stop

ZStat

P value

FDR

PHGDH

1

120202421

120286838

9.07

5.76 × 10−20

1.06 × 10−15

HMGCS2

1

120290619

120311528

6.17

3.39 × 10−10

3.13 × 10−06

REEP3

10

65281123

65384883

5.97

1.20 × 10−09

7.42 × 10−06

SLC6A20

3

45796942

45838027

5.74

4.82 × 10−09

2.23 × 10−05

TTC39B

9

15163620

15307358

5.28

6.58 × 10−08

2.43 × 10−04

GCKR

2

27719709

27746554

4.96

3.56 × 10−07

1.10 × 10−03

DCDC1

11

30851916

31391357

4.79

8.54 × 10−07

2.25 × 10−03

ZAP70a

2

98330023

98356325

4.76

9.73 × 10−07

2.25 × 10−03

MXRA7

17

74668633

74707098

4.73

1.10 × 10−06

2.26 × 10−03

PSPH

7

56078744

56119297

4.71

1.23 × 10−06

2.28 × 10−03

  1. Top ten genes enriched with SNPs signals (MAGMA). aLies outside the MacTel-associated loci.