Fig. 5: Interferon alpha signaling genes are significantly upregulated in juvenile SARS-CoV-2-infected macaques but not old SARS-CoV-2-infected macaques. | Communications Biology

Fig. 5: Interferon alpha signaling genes are significantly upregulated in juvenile SARS-CoV-2-infected macaques but not old SARS-CoV-2-infected macaques.

From: IFN signaling and neutrophil degranulation transcriptional signatures are induced during SARS-CoV-2 infection

Fig. 5

a Differential expression significance values for genes from the “Interferon-alpha signaling” (R-HSA-909733) pathway, in both the juvenile vs naive and old vs naive comparisons. Included are significance values for all genes (gray), pathway genes significantly upregulated in juvenile but not old (orange) and other pathway genes (green). P value cutoffs (0.01 and 0.1) are indicated with dashed lines. b The relative expression levels (FPKM) for the five “interferon-alpha signaling” genes belonging to this gene set are shown. P values represent FDR-corrected significance values from DESeq2.

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