Fig. 6: Genes related to VEGF signaling are downregulated in old macaques compared to juvenile macaques during COVID-19.

The top 20 most significantly a upregulated genes and b downregulated genes in infected old macaque lungs but not in juvenile macaques. Expression values are visualized by Z scores of normalized expression data (FPKM) per sample, and Log2 fold change and -Log P values are from the DESeq2 output. Genes are sorted by P value.