Fig. 7: VEGF pathway genes are significantly downregulated in old SARS-CoV-2- infected macaques but not juvenile SARS-CoV-2-infected macaques. | Communications Biology

Fig. 7: VEGF pathway genes are significantly downregulated in old SARS-CoV-2- infected macaques but not juvenile SARS-CoV-2-infected macaques.

From: IFN signaling and neutrophil degranulation transcriptional signatures are induced during SARS-CoV-2 infection

Fig. 7

a Differential expression significance values for genes from the “Signaling by VEGF” (R-HSA-194138) pathway, in both the juvenile vs naive and old vs naive comparisons. Included are significance values for all genes (gray), pathway genes significantly downregulated in old but not juvenile (orange) and other pathway genes (green). P value cutoffs (0.01 and 0.1) are indicated with dashed lines. b The relative expression levels (FPKM) for the seven “Signaling by VEGF” genes belonging to this gene set are shown. P values represent FDR-corrected significance values from DESeq2.

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