Fig. 2: Heavy and light chain diversity accumulation curves.
From: A single donor is sufficient to produce a highly functional in vitro antibody library
a Species accumulation curves for HCDR3 at varying hamming distance criteria reveal continued accumulation at all edit string distance cutoffs (Hamming 0–3) and using accumulation cutoffs (N ≥ 2). b Species accumulation curves of light chain CDR3 at varying hamming distance criteria reveal saturation of diversity around 7–8 × 105 for the combined heavy and light chain for hamming distances 1–3 and for abundance cutoffs of N ≥ 2.
