Fig. 3: Analysis of the dissociation kinetics of the β3 integrin/talin/paxillin complex. | Communications Biology

Fig. 3: Analysis of the dissociation kinetics of the β3 integrin/talin/paxillin complex.

From: Structural and functional analysis of LIM domain-dependent recruitment of paxillin to αvβ3 integrin-positive focal adhesions

Fig. 3

a, d, g Experimental dissociation kinetics of a β3_PA-GFP integrins from mCherry_paxillin-positive FAs and of d PA-GFP_talin and g PA-GFP_paxillin from β3_mCherry-positive FAs. b, e, h Box plot of the half-lives of b β3_PA-GFP integrins in mCherry_paxillin-positive FAs and of e PA-GFP_talin and h PA-GFP_paxillin in β3_mCherry-positive FAs. Statistical analysis is provided in Supplementary Dataset 4. c, f, i Representative images of photoactivation time series of experiments in a, b, d, e, and f, g. ns (not significant) p > 0.05; *p ≤ 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001. Sample size, complete statistical analysis, and p values are provided in tables in supplementary datasets.

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