Fig. 5: C10-specific signature is conserved in multiple tissue ADCs and it is associated with lower overall survival.
From: Identification of a targetable KRAS-mutant epithelial population in non-small cell lung cancer
a Boxplots for distributions of the signature scores for combining the positive and negative signature genes over KRAS-mutant samples versus WT samples cross four adenocarcinomas (colon, COAD, N = 100 mutant KRAS and N = 211 WT; pancreas, PAAD, N = 127 mutant KRAS and N = 31 WT; stomach, STAD, N = 18 mutant KRAS and N = 294 WT). P values are indicated. b Survival analysis between C10 signature high and low groups (p value = 1.96 × 10−6, hazard ratio = 2.37). C10 low group: n = 223, and C10 high group: n = 222.
