Fig. 3: Cytokines induced FGL2 expression via different pathways in Tregs. | Communications Biology

Fig. 3: Cytokines induced FGL2 expression via different pathways in Tregs.

From: Regulatory T cells induce polarization of pro-repair macrophages by secreting sFGL2 into the endometriotic milieu

Fig. 3

a Tregs were isolated and stimulated with indicated cytokines. FGL2 mRNA was examined by qRT-PCR after 24 h, the concentration of FGL2 in the supernatant was detected by ELISA. b Predicted binding sites of transcription factors STAT1, NF-κB, and C/EBPα on the FGL2 promoter region. c–e Differentially expressed NF-κB (c), STAT1 (d), and C/EBPα (e) genes in Tregs treated with indicated cytokines. Data represent the mean value ± SEM of five individual experiments (n = 5).

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