Fig. 5: Tregs promoted pro-repair macrophages polarization via secreting sFGL2. | Communications Biology

Fig. 5: Tregs promoted pro-repair macrophages polarization via secreting sFGL2.

From: Regulatory T cells induce polarization of pro-repair macrophages by secreting sFGL2 into the endometriotic milieu

Fig. 5

Macrophages (MФ) were indirectly co-cultured with Tregs by transwell, recombinant human FGL2 (rhFGL2), or anti-FGL2 antibody were added separately. The expression of CD86, HLA-DR, CD163, CD206, IL-6, TGF-β1 were analyzed by FCM (a–d). The production of IL-12p70 and IL-10 were detected by ELISA (b, d). Data represent the mean value ± SEM of three individual experiments (n = 3).

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