Fig. 6: FGL2 induced pro-repair macrophages polarization through the suppression of the NF-κB signaling pathway and the activation of the SHP2-ERK1/2-STAT3 signaling pathway. | Communications Biology

Fig. 6: FGL2 induced pro-repair macrophages polarization through the suppression of the NF-κB signaling pathway and the activation of the SHP2-ERK1/2-STAT3 signaling pathway.

From: Regulatory T cells induce polarization of pro-repair macrophages by secreting sFGL2 into the endometriotic milieu

Fig. 6

THP-1 and U937 cells were treated with rFGL2 (a, b) or SHPi/ERKi (c). The phosphorylation levels of NF-κB, ERK1/2, STAT3, and SHP2 in THP-1 and U937 cells were determined by western blot (a–c). Data represent the mean value ± SEM of three individual experiments (n = 3).

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