Fig. 4: Binding affinity of SARS-CoV-2 S-RBD, S1 and S-trimer.
From: Human ACE2 receptor polymorphisms and altered susceptibility to SARS-CoV-2
a–c ELISA assay measuring the affinity of indicated ACE2 WT or variants for SARS-CoV-2 S-RBD (a), S1 (b) and S-trimer (c). d–i Sensorgrams for the binding of a 3-fold dilution series of monomeric and dimeric ACE2 variants to streptavidin-captured SARS-CoV-2 RBD are provided (black). Fits to the empirical binding curves are shown overlaid (red).
