Fig. 5: ACE2 variants block pseudotyped SARS-CoV-2 virus infection.
From: Human ACE2 receptor polymorphisms and altered susceptibility to SARS-CoV-2
Inhibition of pseudovirus entry into HEK293T cells by ACE2 WT and mutants S19P, T92I, and K26R. A range of seven different concentrations of Fc-tagged ACE2 proteins were mixed with pseudoviruses and the infectivity was measured by the luciferase signal as an indication of the amount of virus entering the cells. Data are presented as the mean ± SD (standard deviation). Sample size n = 3.
