Table 2 Association of LTL-associated low-frequency variants with mortality in the SCHS dataset.
From: Low frequency variants associated with leukocyte telomere length in the Singapore Chinese population
rs79314063 | rs79617270 | rs139620151 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Case/non-case | Test allele | HR (95% Cl) | P | Padj | Test allele | HR (95% Cl) | P | Padj | Test allele | HR (95% Cl) | P | Padj | |
All cause mortality | 7743/17,807 | G | 0.906 (0.743, 1.105) | 0.329 | 1.000 | G | 1.177 (0.979, 1.415) | 0.083 | 0.747 | A | 1.018 (0.786, 1.318) | 0.891 | 1.000 |
Cancer mortality | 2617/22,933 | 1.109 (0.815, 1.510) | 0.511 | 1.000 | 1.544 (1.173, 2.032) | 0.002 | 0.018 | 0.805 (0.492, 1.316) | 0.387 | 1.000 | |||
Cardiovascular mortality | 2345/23,205 | 0.524 (0.326, 0.843) | 0.008 | 0.072 | 0.965 (0.666, 1.397) | 0.849 | 1.000 | 1.052 (0.661, 1.672) | 0.832 | 1.000 | |||
Ischemic heart disease mortality | 1341/23,205 | 0.582 (0.322, 1.049) | 0.072 | 0.648 | 0.905 (0.545, 1.501) | 0.699 | 1.000 | 0.909 (0.472, 1.751) | 0.775 | 1.000 | |||
Stroke mortality | 599/23,205 | 0.489 (0.184, 1.299) | 0.151 | 1.000 | 0.922 (0.440, 1.934) | 0.831 | 1.000 | 1.562 (0.741, 3.291) | 0.241 | 1.000 | |||
Respiratory mortality | 1624/23,926 | 0.943 (0.615, 1.446) | 0.787 | 1.000 | 0.887 (0.551, 1.427) | 0.621 | 1.000 | 1.454 (0.889, 2.381) | 0.136 | 1.000 | |||
