Fig. 1: The essentiality of mitochondrial genes in tumour cells. | Communications Biology

Fig. 1: The essentiality of mitochondrial genes in tumour cells.

From: Genome-wide CRISPR/Cas9 deletion screen defines mitochondrial gene essentiality and identifies routes for tumour cell viability in hypoxia

Fig. 1

a Schematic diagram shows our analysis pathway for using the Achilles cancer dependency map (DepMap) gene essentiality data. b Pie charts show the percentage of common essential genes (shown in yellow) among mitochondrially expressed genes (left chart), and among all genes screened (right chart) in (a). Other (non-common essential) genes (shown in blue). c List of common essential mitochondrially expressed genes identified in (a), grouped by functional annotation. (*) indicates genes with multiple functions.

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