Table 1 Identification of clusters as specific types of tumor and stromal cells.
Cluster | Cell-type designation | Distinctive markers |
---|---|---|
0 | Early differentiating CGNP-like tumor cells | Pde1c, Nhlh1/2 |
1 | Proliferative, quiescent tumor cells | Hes1, Ccnd1 |
2 | Proliferative, quiescent tumor cells | Srebf1, Ccnd2 |
3 | Proliferative, quiescent tumor cells | Srebf1, Ccnd1 |
4 | Proliferative, cycling tumor cells | Top2a, Lig1, Esco2 |
5 | Differentiating CGNP-like tumor cells | Mtss1, Cntn2 |
6 | Proliferative, cycling tumor cells | Hells, Rrm2 |
7 | Proliferative, cycling tumor cells, M-phase enriched | Cdc20, Cenp1 |
8 | Proliferative, cycling tumor cells, M-phase enriched | Aspm, Ccnb1 |
9 | Late differentiating CGN-like | Pcp4, Car10 |
10 | Differentiating CGN-like tumors | Cntn2, Nhlh1 |
11 | Proliferative, cycling tumor cells | Hells, Lig1, Pclaf |
12 | Proliferative, cycling tumor cells | Hells, Lig1, Gli1 |
13 | CGNs and CGN-differentiated tumor cells | Gabra6, Vsnl1 |
14 | Oligodendrocytes | Ptpz1, Sox10, Fabp7, Olig1/2 |
15 | M2 microglia/macrophages | Mrc1, C1qb, Aif |
16 | Astrocytes | Aldoc, Aqp4, Fabp7 |
17 | Fibroblasts | Lum, Vtn |
18 | Endothelial cells | Cldn5, Flt1 |
19 | M1 microglia/macrophages | Selplg, Siglech, C1qa, Aif |
20 | Ependymal/choroid plexus cells | Rsph1, Folr1 |
21 | Myelinating oligodendrocytes | Opalin, Plp |