Table 1 Identification of clusters as specific types of tumor and stromal cells.

From: Cryptic developmental events determine medulloblastoma radiosensitivity and cellular heterogeneity without altering transcriptomic profile

Cluster

Cell-type designation

Distinctive markers

0

Early differentiating CGNP-like tumor cells

Pde1c, Nhlh1/2

1

Proliferative, quiescent tumor cells

Hes1, Ccnd1

2

Proliferative, quiescent tumor cells

Srebf1, Ccnd2

3

Proliferative, quiescent tumor cells

Srebf1, Ccnd1

4

Proliferative, cycling tumor cells

Top2a, Lig1, Esco2

5

Differentiating CGNP-like tumor cells

Mtss1, Cntn2

6

Proliferative, cycling tumor cells

Hells, Rrm2

7

Proliferative, cycling tumor cells, M-phase enriched

Cdc20, Cenp1

8

Proliferative, cycling tumor cells, M-phase enriched

Aspm, Ccnb1

9

Late differentiating CGN-like

Pcp4, Car10

10

Differentiating CGN-like tumors

Cntn2, Nhlh1

11

Proliferative, cycling tumor cells

Hells, Lig1, Pclaf

12

Proliferative, cycling tumor cells

Hells, Lig1, Gli1

13

CGNs and CGN-differentiated tumor cells

Gabra6, Vsnl1

14

Oligodendrocytes

Ptpz1, Sox10, Fabp7, Olig1/2

15

M2 microglia/macrophages

Mrc1, C1qb, Aif

16

Astrocytes

Aldoc, Aqp4, Fabp7

17

Fibroblasts

Lum, Vtn

18

Endothelial cells

Cldn5, Flt1

19

M1 microglia/macrophages

Selplg, Siglech, C1qa, Aif

20

Ependymal/choroid plexus cells

Rsph1, Folr1

21

Myelinating oligodendrocytes

Opalin, Plp