Fig. 1: Chemical and optical analyses of CLP-PEG-MPC and CLP-PEG hydrogels. | Communications Biology

Fig. 1: Chemical and optical analyses of CLP-PEG-MPC and CLP-PEG hydrogels.

From: Collagen analogs with phosphorylcholine are inflammation-suppressing scaffolds for corneal regeneration from alkali burns in mini-pigs

Fig. 1

a Fourier transformed infrared spectroscopy shows the incorporation of the CLP-PEG monomer (lavender line) into the CLP-PEG hydrogel (black line) the CLP-PEG monomer and MPC monomer (purple line) into the CLP-PEG-MPC hydrogel (pink line). b 31P NMR spectroscopy with peaks that show the incorporation of phosphorylcholine (purple line) into CLP-PEG-MPC hydrogels (pink line) (n=1, per group). c Both CLP-PEG (black line) and CLP-PEG-MPC (pink line) hydrogels transmit the full spectrum of visible light, but CLP-PEG-MPC blocks short UV wavelengths (n=1, per group). d, e Apparent and cumulative permeability of 700 Da Alexa Fluor® 568 hydrazide sodium salt through CLP-PEG-MPC hydrogels (pink squares, n=4 technical replicates (TR)) in comparison to 12 and 8% CLP-PEG (black circles, n=4; light blue triangles, n=3 TR, respectively) hydrogels and hAM (gray inverted triangles, n=3 TR). f Both CLP-PEG-MPC (pink squares) and CLP-PEG hydrogels (black circles) remained stable and minimally degraded when exposed to collagenase enzyme (n=3 TR per group).

Back to article page