Fig. 1: Subcellular distribution of AGO2. | Communications Biology

Fig. 1: Subcellular distribution of AGO2.

From: AGO2 localizes to cytokinetic protrusions in a p38-dependent manner and is needed for accurate cell division

Fig. 1

a Representative immunofluorescence images of the NTHY ori 3-1 cells (scale bar: 40 μm). Three types of AGO2 cellular protrusions are presented: b the typical Actin-filopodial structure (scale bar: 20 μm), c the open-ended tunneling nanotube (scale bar: 20 μm), and d the close-ended tubes (scale bar: 20 μm). AGO2 was depicted in green, F-Actin in red (Texas red-phalloidin), and nuclei in blue (DAPI). 3D surface reconstruction of time points from time-lapse experiments of AGO2-GFP expressing cells; e, f open-ended tubes and g, h close-ended tubes, processed by Imaris software. Surfaces are color-coded (blue to red) according to speed (low to high), showcasing the motility of the respective objects. The scale bar is 20 μm.

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