Fig. 5: α-Tubulin alterations and cytoskeletal changes influence AGO2 localization. | Communications Biology

Fig. 5: α-Tubulin alterations and cytoskeletal changes influence AGO2 localization.

From: AGO2 localizes to cytokinetic protrusions in a p38-dependent manner and is needed for accurate cell division

Fig. 5

Representative images of NTHY ori 3-1 cells a before treatment with Demecolcine (Dem) and at b, c 5 h, and d, e 7 h after treatment. a, b, d, f, g AGO2 was stained green, a–g α-Tubulin red and c, e CITK green. Nuclei of cells were visualized in blue (DAPI). The scale bar is 20 μm. 3D surface reconstruction by Imaris of the cytokinetic bridges f before (scale bar: 15 μm) and g after Demecolcine treatment (scale bar: 10 μm).

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