Table 1 Characteristics of carbapenem-resistant K. pneumoniae 17ZR-91 and corresponding transconjugants.

From: Clinical evolution of ST11 carbapenem resistant and hypervirulent Klebsiella pneumoniae

Strain ID

Species

ST

MIC (µg mL−1)

 

rmpA2, blaKPC-2

Conjugation efficiency

IMP

ETP

MRP

CTX

CAZ

ATM

AMK

CIP

TIG

PB

TE

17ZR-91

K. pneumoniae

ST86

4

32

2

32

16

128

1

0.03

0.5

1

>128

+

NA

EC600

E. coli

–

0.25

0.015

0.03

0.06

0.5

0.12

0.5

0.12

0.5

0.5

2

−

NA

EC600-TC

E. coli

–

4

8

2

16

8

64

0.5

0.12

0.25

0.5

64

+

1.67E-08

KP04-1

K. pneumoniae

ST11

0.12

0.5

0.06

>128

>128

>128

16

>32

2

1

1

−

NA

KP04-1-TCa

K. pneumoniae

ST11

16

16

8

>128

>128

>128

16

32

0.5

1

128

+

4.58E–06

KP04-1-TC1

K. pneumoniae

ST11

16

16

8

>128

>128

>128

16

>32

0.5

1

128

+

2.43E–06

KP04-1-TC2

K. pneumoniae

ST11

16

16

8

>128

>128

>128

16

>32

0.5

1

128

+

2.43E–06

  1. ‘NA’ indicates that the test or analysis was not conducted on this strain.
  2. KP04-1-TC1 and KP04-1-TC2 are two different transconjugant colonies from the conjugation experiments.
  3. CAZ ceftazidime, CTX cefotaxime, IMP imipenem, MRP meropenem, ETP ertapenem, AMK, amikacin, CIP ciprofloxacin, PB polymyxin B, ATM aztreonam, TE tellurite, TIG tigecycline.
  4. aTransconjugants obtained using E. coli EC600-TC as donor.
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