Fig. 3: ATAC-seq and sequence conservation analysis for the herring TSHR locus.

a ATAC-seq signals in herring hypothalamus and saccus vasculosus (BSH) and brain without BSH (brain). Genomic locations of two annotated genes at this locus, CEP128 and TSHR, are indicated together with the six highly differentiated variants between spring- and autumn-spawning herring, including two non-coding SNPs (SNP1 and 2), two coding SNPs (SNP3 and 4), the 5.2 kb BEL/Pao structural variant and the 22aa copy number variant at the C terminus of herring TSHR. b Sequence conservation represented by the phastCons score calculated using data from 12 fish species.