Fig. 4: Knockout of BRPF1 suppressed HCC growth in vivo.
From: Bromodomain-containing protein BRPF1 is a therapeutic target for liver cancer
a BRPF1 knockout reduced subcutaneous tumor growth in nude mice. The tumor volumes and tumor weights between two groups were compared by paired t-test. n = 9 b Knockout of BRPF1 dramatically suppressed HCC orthotopic tumor growth in the liver and lung metastasis in nude mice. Data were compared by independent t-test. n = 6 *P < 0.05, **P < 0.01 vs. sgNTC as indicated.
