Fig. 4: Correlation of brain activity with hair lead (Pb) levels (N = 892).
From: Lead exposure is associated with functional and microstructural changes in the healthy human brain
a Regions with significant correlations between the brain activity of the contrast (2-back–0-back) and hair lead levels are overlaid on a single-subject T1 image from SPM8 (the image file with the name of “single_subje_T1”). Results were obtained using a threshold-free cluster enhancement of p < 0.025 based on 5000 permutations. The color bar represents the TFCE score. It reflects both voxel’s height and the sum of the spatially contiguous voxels supporting it; therefore, it reflects both the strength and extent of effects. Significant positive correlations were found in the presupplementary motor area and right middle and superior frontal gyrus. b Scatter plot of the association between hair lead levels and mean beta estimates in the larger clusters in (a).
