Table 3 Brain regions exhibiting significant negative correlations between hair lead level and mean diffusivity.
From: Lead exposure is associated with functional and microstructural changes in the healthy human brain
No. | Included gray-matter areasa (number of significant voxels in the left and right sides of each anatomical area) | Included large bundlesb (number of significant voxels in the left and right sides of each anatomical area) | x | y | z | TFCE value | Part correlation coefficient | Corrected p value (FWE) | Cluster size (mm3) |
|---|---|---|---|---|---|---|---|---|---|
(1) | Angular gyrus (L:15)/inferior frontal operculum (L:180)/inferior frontal triangular (L:228)/middle frontal other areas (L:998)/superior frontal other areas (L:471)/Heschl gyrus (L:89)/hippocampus (L:87)/insula (L:481)/paracentral lobule (L:187)/inferior parietal lobule (L:467)/superior parietal lobule (L:132)/postcentral gyrus (L:1979)/precentral gyrus (L:2279)/precuneus (L:9)/Putamen (L:181)/Rolandic operculum (L:442)/supplemental motor area (L:6)/supramarginal gyrus (L:888)/inferior temporal gyrus (L:87)/middle temporal gyrus (L:1064)/superior temporal gyrus (L:836)/thalamus (L:230) | Posterior limb of the internal capsule (L:43)/retrolenticular part of the internal capsule (L:548)/anterior corona radiata (L:29)/superior corona radiata (L:43)/posterior thalamic radiation (L:9)/sagittal stratum (L:103)/external capsule (L:383)/Stria terminalis (L:112)/superior longitudinal fasciculus (L:805)/inferior fronto-occipital fasciculus (L:108) | −42 | −13.5 | 31.5 | 2509.93 | −0.150 | 0.002 | 51036.75 |
(2) | Fusiform gyrus (L:465)/parahippocampal gyrus (L:20)/inferior temporal gyrus (L:13)/cerebellum (L:219) | None | −33 | −39 | −30 | 1382.16 | −0.128 | 0.016 | 2338.875 |
(3) | Inferior temporal gyrus (L:47) | None | −49.50 | −36 | −7.5 | 1249.67 | −0.091 | 0.023 | 40.5 |
(4) | Middle temporal gyrus (L:3) | None | −48 | −33 | −25.5 | 1242.95 | −0.118 | 0.023 | 158.625 |
