Table 4 Brain regions exhibiting significant positive correlations between hair lead level and brain activity.

From: Lead exposure is associated with functional and microstructural changes in the healthy human brain

No.

Included gray-matter areasa (number of significant voxels in the left and right sides of each anatomical area)

x

y

z

TFCE value

Part correlation coefficient

Corrected p value (FWE)

Cluster size (mm3)

Activated areas, deactivated areas in the 2-back–0-back contrastb

1

Middle cingulum (R:6)/superior frontal medial area (R:3)/supplemental motor area (L:100, R:72)

0

9

57

775.37

0.169

0.006

4671

100%, 0%

2

Middle frontal other areas (R:25)/superior frontal other areas (R:61)

33

6

33

625.11

0.163

0.018

2187

100%, 0%

  1. aThe labels of the anatomical regions of gray matter were based on the WFU PickAtlas Tool (http://www.fmri.wfubmc.edu/cms/software#PickAtlas/)96, 97 and the PickAtlas automated anatomical labeling Atlas option98. Temporal pole areas and some other areas included all subregions in the areas of this Atlas.
  2. bPercentage of voxels activated or deactivated in the contrast (2-back–0-back) in our previous study at a threshold of P < 0.05, corrected for FDR26.
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