Fig. 5: Coordinated electrical activities in colonic smooth muscle during maintained colonic distension with a metal rod of uniform diameter inserted through the lumen. | Communications Biology

Fig. 5: Coordinated electrical activities in colonic smooth muscle during maintained colonic distension with a metal rod of uniform diameter inserted through the lumen.

From: Long range synchronization within the enteric nervous system underlies propulsion along the large intestine in mice

Fig. 5

a Photomicrograph of the preparation of mouse colon with metal rod (inner diameter 2.41 mm through the lumen. The two electrodes are shown separated by 30 mm, one in the proximal-mid colon, the other in the distal colon. b shows simultaneous electrical recordings from the proximal and distal colon in the presence of nicardipine, where a coordinated burst of EJPs discharges at both electrodes. The periods represented by the bars labelled 1 and 2 are shown on expanded scale in c and e, respectively. d shows high temporal synchrony between EJPs, while a few seconds later in e, the EJPs are phase shifted by about 100 ms.

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