Fig. 5: Single-cell RNA sequencing shows that bintrafusp alfa responders have increased infiltrating NK and T cells and decreased tumor cells compared to nonresponders. | Communications Biology

Fig. 5: Single-cell RNA sequencing shows that bintrafusp alfa responders have increased infiltrating NK and T cells and decreased tumor cells compared to nonresponders.

From: Distinct immune microenvironment profiles of therapeutic responders emerge in combined TGFβ/PD-L1 blockade-treated squamous cell carcinoma

Fig. 5

a Combined UMAP clusters of cells from A223 tumors in bintrafusp alfa responders (n = 2) and nonresponders (n = 2) after cluster phenotyping. b Each cluster from (a) represented as a proportion of total responder cells (blue) and nonresponder cells (red).

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