Fig. 3: The G protein-coupled receptor, NPR-10, is required for the male behavioral response to ascr#8.
From: Distinct neuropeptide-receptor modules regulate a sex-specific behavioral response to a pheromone
a FLP-3 peptide affinities for known receptors, adapted from Li and Kim, 201423. b, c Male raw dwell time and log(fold-change) values for npr receptor mutants and npr-10 rescue in the SWAA, respectively. d npr-10 males exhibit increased avoidance to ascr#8 compared to the other receptors. Expression of npr-10 under its endogenous promoter rescues the avoidance phenotype. e Localization of pnpr-10::npr-10::GFP in the amphid region of the male head. Neurons expressing npr-10 include the inner labial neurons, IL2, and their respective socket cells (ILso), the interneurons RMEV and RMEL, the chemosensory neurons ADL and ASG, as well as the interneurons AVF and AVK. f Expression of pnpr-10::npr-10::GFP in the mail tail. Localization is observed in the B-class Ray neurons. ♂ denotes male data.
