Fig. 4: Tumor and peri-tumoral tissues have distinct metabolic states as revealed by NMR spectroscopy analysis.
From: Nrf2 activation does not affect adenoma development in a mouse model of colorectal cancer
a Principal component analysis (PCA) score plot from NMR data for total fatty acids (R2 = 75.9% and Q2 = 41.7%). At least seven independent biological replicates of colon tissue from peri-tumorous (red) and tumorous (black) tissues were included. b Plot showing the individual metabolites driving the separation among the tissue types (loadings), with the variables (i.e., metabolites) represented in green circles (Asp = aspartate and Asn = asparagine).
