Fig. 5: The tumor microbiome is associated with host functional modules.

a Heatmap of Pearson’s correlation between 21 functional modules (columns) and 43 bacterial genera (rows). The color represents the coefficient of correlation. + denotes the p values <0.05, and * denotes the p values <0.01. b Correlation network between 4 functional modules and 3 key genera refined from (a). Red and blue edges denote Pearson’s correlation coefficients >0.3 and <−0.3, respectively.