Fig. 6: STZ leads to increased tau phosphorylation in frontal cortex (including ACC) and hippocampus. | Communications Biology

Fig. 6: STZ leads to increased tau phosphorylation in frontal cortex (including ACC) and hippocampus.

From: Altered theta rhythm and hippocampal-cortical interactions underlie working memory deficits in a hyperglycemia risk factor model of Alzheimer’s disease

Fig. 6

a, b Tau levels at Ser396 were significantly elevated in the hippocampus (a) and frontal cortex (b). Proportions of pTau396 normalized to total tau are on the y-axes. Dots show individual data points (see “Methods”). Saline control values are in gray and STZ in magenta. Representative western blot images are shown in the insets. *p < 0.05; ***p < 0.001. Error bars = SEM.

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