Fig. 4: Association with diseases, molecular functions, and physiologic systems.

The 284 candidate causal PLT genes (Supplementary Data 16) were analyzed for association with diseases, molecular functions, and physiologic systems, using the Ingenuity Pathway Analysis (see “Methods”). Shown are P values of the identified associations along with median and interquartile ranges for each group (boxplots). Dark red dots represent individual associations, and black dots indicate outliers. For details on associations, see Supplementary Data 17.