Fig. 1: Number of samples and mutated genes per cancer type.
From: A systematic analysis of genetic interactions and their underlying biology in childhood cancer
a, b The number of samples per cancer type in the DKFZ (a) and TARGET (b) data sets used in this study before sample filtering (e.g., removal of hypermutators and relapse tumors). c, d Number of mutated genes identified in each individual tumor per cancer type for the DKFZ (c) and TARGET (d) data sets after sample filtering. Box-plots’ center line: median; box limits: upper and lower quartiles; lower (higher) whisker: smallest (largests) observation greater (less) than or equal to lower (higher) box limit—(+) 1.5× interquartile range. Points on the horizontal axis represent tumor samples without any mutated genes. Mutated genes are defined as genes that harbor at least one exonic mutation with a likely functional consequence. Only SNVs and small indels were considered. Source data underlying Fig. 1 can be found in Supplementary Data 2.
