Fig. 3: Candidate gene pairs resulting from the genetic interaction detection pipeline.
From: A systematic analysis of genetic interactions and their underlying biology in childhood cancer

Graph depicting candidate genetic interactions found in either TARGET (red boxes) or DKFZ (blue boxes). Mutually exclusive pairs are indicated in red, co-occurring pairs in blue. SMG significantly mutated genes. “reported previously” refers to gene pairs that were detected as significantly co-occurring or mutually exclusive in the studies accompanying the TARGET7 and DKFZ6 data sets. Source data underlying Fig. 3 can be found in Supplementary Data 1.