Fig. 4: Down-sampling the TARGET data set greatly reduces the number of candidates.
From: A systematic analysis of genetic interactions and their underlying biology in childhood cancer
Number of candidate pairs for the WeSME test on TARGET cancer types B-ALL, T-ALL, AML, and WT using either all samples, or down-sampled data sets. Dots represent the number of candidates for each of the ten replicates per sample size. Diamonds indicate the number of high confident candidates (being a significant candidate in at least nine out of ten tests). The first category (all samples) shows for each cancer type the original number of samples in the TARGET and -in parentheses- in the DKFZ data set. Source data underlying Fig. 4 can be found in Supplementary Data 2.
