Fig. 3: Graphical representation of differentially expressed genes (DEG).

a Heatmap of DEGs between normal bone (N-) and canine osteosarcoma samples (T-). b–d Heatmaps of core-enriched genes associated with three significantly enriched Hallmark gene sets (epithelial to mesenchymal transition, glycolysis and myogenesis), as identified by GSEA analysis. These genes were differentially expressed in tumor samples when compared to normal bone. The heatmap scale represents row z-score.