Table 3 Univariate Cox Proportional Hazard Modelling.
Variable | Group | Median survival time | Percent survival—1 year | Percent survival—2 years | HR | 95% CI | p value |
|---|---|---|---|---|---|---|---|
TP53 mutation status | Mut | 296 | 47 | 12 | 0.21 | 0.08 to 0.58 | 0.002 |
WT/NULL | 95 | 14 | 0 | ||||
Tumor location—Humerus | Yes | 114 | 12.5 | 0 | 4.05 | 1.51 to 10.84 | 0.005 |
No | 372 | 50 | 13 | ||||
Pre-treatment peripheral blood monocytes (>or< 0.4 × 103 cells/µl) | High | 216 | 20 | 0 | 2.12 | 0.87 to 8.14 | 0.091 |
Low | 309 | 50 | 14 | ||||
Alkaline phosphatase levels (>or< 140 units/liter) | High | 216 | 29 | 0 | 1.93 | 0.74 to 4.99 | 0.176 |
Normal | 246 | 35 | 6 | ||||
IHC CD3 staining | NA | NA | NA | NA | 0.56 | 0.23 to 1.33 | 0.191 |
Age | NA | NA | NA | NA | 1.13 | 0.93 to 1.36 | 0.224 |
Sex | Male | 296 | 42 | 8 | 0.75 | 0.33 to 1.72 | 0.504 |
Female | 142 | 33 | 8 | ||||
Weight | NA | NA | NA | NA | 1 | 0.97 to 1.04 | 0.846 |
IHC MAC387 staining | NA | NA | NA | NA | 1.02 | 0.61 to 1.69 | 0.954 |
